EIDD 1931

Name: EIDD 1931
Brand: Tocris Bioscience
SKU: 7231

Tocris Bioscience, part of Bio-Techne | Catalog # 7231

COA / SDS

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside

Key Product Details

Chemical Name:	N-Hydroxycytidine
Purity:	≥98%

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Technical Data
Citations

Biological Activity for EIDD 1931

EIDD 1931 is a viral RNA-dependent RNA polymerase (RdRP) inhibitor and broad spectrum antiviral nucleotide. Inhibits replication of a range of RNA viruses including influenza, Ebola, HCV, and human and zoonotic coronaviruses (IC₅₀ values are 0.15 and 0.3 μM for inhibition of MERS-CoV and SARS-CoV-2 replication in vitro). Increases mutation rates and induces lethal mutagenesis in viral RNA. Also inhibits replication of mouse hepatitis virus with mutations conferring resistance to remdesivir (Cat. No. 7226).

Technical Data for EIDD 1931

Formula	C₉H₁₃N₃O₆
Storage	Store at -20°C
Purity	≥98%
CAS Number	3258-02-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for EIDD 1931

Solubility

Soluble Soluble to 100 mM in DMSO and to 50 mM in water

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References for EIDD 1931

References are publications that support the biological activity of the product.

Urakova et al. β-d-N⁴-hydroxycytidine is a potent anti-alphavirus compound that induces a high level of mutations in the viral genome. J.Virol., 2018;92 PMID: 29167335
Sheahan et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci.Transl.Med., 2020;12 PMID: 32253226

EIDD 1931

Tocris Bioscience, part of Bio-Techne | Catalog # 7231

Key Product Details

Biological Activity for EIDD 1931

Technical Data for EIDD 1931

Solubility for EIDD 1931

Dilution Calculator

Reconstitution Calculator

References for EIDD 1931

Product Documents for EIDD 1931

COA

Certificate of Analysis

SDS

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