Eticlopride hydrochloride

Name: Eticlopride hydrochloride
Brand: Tocris Bioscience
SKU: 1847

Tocris Bioscience, part of Bio-Techne | Catalog # 1847

(1)

Citations (26)

COA / SDS

D2 and D3 antagonist (D3 > D2)

Key Product Details

Chemical Name:	3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride
Purity:	≥99%
Molecular Weight:	377.31 kDa

View Full Technical Details for Eticlopride hydrochloride

Technical Data
Citations / Reviews (1)

Biological Activity for Eticlopride hydrochloride

Eticlopride hydrochloride is a selective dopamine D₂/D₃ receptor antagonist (K_i values are 0.50 and 0.16 nM respectively). Antipsychotic.

Technical Data for Eticlopride hydrochloride

M. Wt	377.31 kDa
Formula	C₁₇H₂₅ClN₂O₃.HCl
Storage	Desiccate at RT
Purity	≥99%
CAS Number	97612-24-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Eticlopride hydrochloride

Solubility

Soluble Soluble to 100 mM in water

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References for Eticlopride hydrochloride

References are publications that support the biological activity of the product.

Hall et al. Some in vitro receptor binding properties of [³H]eticlopride, a novel substituted benzamide, selective for DA-D₂ receptors in the rat brain. Eur.J.Pharmacol., 1985;111:191 PMID: 4018125
Giuliani and Ferrari Involvement of DA receptors in the antipsychotic profile of (-) eticlopride. Physiol.Behav., 1997;61:563 PMID: 9108576
Claytor et al. The effects of eticlopride and the selective D₃-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacol.Biochem.Behav., 2006;83:456 PMID: 16631246