Flupenthixol dihydrochloride

Name: Flupenthixol dihydrochloride
Brand: Tocris Bioscience
SKU: 4057

Tocris Bioscience, part of Bio-Techne | Catalog # 4057

Citations (17)

COA / SDS

Dopamine antagonist

Key Product Details

Description:	Dopamine antagonist
Alternative Names:	Flupentixol
Chemical Name:	4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	507.44

View Full Technical Details for Flupenthixol dihydrochloride

Technical Data
Citations

Biological Activity for Flupenthixol dihydrochloride

Flupenthixol dihydrochloride is an antipsychotic drug. Exhibits antagonistic activity at dopamine D_1-5 receptors. Used in schizophrenia treatment.

This compound is a mixture of E/Z isomers (ratio: 60:40).

Compound Libraries for Flupenthixol dihydrochloride

Flupenthixol dihydrochloride is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for Flupenthixol dihydrochloride

M. Wt	507.44
Formula	C₂₃H₂₅F₃N₂OS.2HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	2413-38-9
PubChem ID	17011
InChi Key	IOVDQEIIMOZNNA-UHFFFAOYSA-N
Smiles	Cl.Cl.OCCN1CCN(CCC=C2C3=CC(=CC=C3SC3=C2C=CC=C3)C(F)(F)F)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Flupenthixol dihydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	50.74	100
	DMSO	25.37	50

Preparing Stock Solutions for Flupenthixol dihydrochloride

The following data is based on the product molecular weight 507.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.97 mL	9.85 mL	19.71 mL
5 mM	0.39 mL	1.97 mL	3.94 mL
10 mM	0.20 mL	0.99 mL	1.97 mL
50 mM	0.04 mL	0.20 mL	0.39 mL

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Reconstitution Calculator

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References for Flupenthixol dihydrochloride

References are publications that support the biological activity of the product.

Peuch Pharmacological properties of new antipsychotic agents: Use of animal models. Neuropharmacology 1981 PMID: 6119637