Foxy 5

Tocris Bioscience, part of Bio-Techne | Catalog # 5461

COA / SDS

Wnt5a peptide mimetic

Key Product Details

Description:	Wnt5a peptide mimetic
Purity:	≥95% (HPLC)
Molecular Weight:	694.77

View Full Technical Details for Foxy 5

Technical Data
Citations

Biological Activity for Foxy 5

Foxy 5 is a Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.

Technical Data for Foxy 5

M. Wt	694.77
Formula	C₂₆H₄₂N₆O₁₂S₂
Single Letter Sequence	MDGCEL (Modifications: Met-1 = N-Formyl)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	881188-51-8
PubChem ID	44628955
InChi Key	WFZPJYYCTSHDJI-ATIWLJMLSA-N
Smiles	[H]N([C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(O)=O)C(=O)[C@H](CCSC)NC=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Foxy 5

Solubility

Soluble to 1mg/ml in PBS (pH 7.4)

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References for Foxy 5

References are publications that support the biological activity of the product.

Säfholm A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J.Biol.Chem. 2006 PMID: 16330545
Säfholm The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin.Cancer Res. 2008 PMID: 18927296