Ionomycin free acid

Name: Ionomycin free acid
Brand: Tocris Bioscience
SKU: 2092
Rating: 5 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2092

(2)

Citations (3)

COA / SDS

Calcium ionophore

Key Product Details

Description:	Calcium ionophore
Chemical Name:	(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
Purity:	≥95% (HPLC)
Molecular Weight:	709.01

View Full Technical Details for Ionomycin free acid

Technical Data
Citations / Reviews (2)

Biological Activity for Ionomycin free acid

Ionomycin free acid is a calcium ionophore; more specific than A23187.

Calcium Salt also available.

Technical Data for Ionomycin free acid

M. Wt	709.01
Formula	C₄₁H₇₂O₉
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	56092-81-0
PubChem ID	6912226
InChi Key	PGHMRUGBZOYCAA-ADZNBVRBSA-N
Smiles	O=C(O)CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C(O)/[C@H](C)C[C@@H](C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@]2([H])O[C@@]([C@H](O)C)(C)CC2)(C)O1)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ionomycin free acid

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	7.09	10

Preparing Stock Solutions for Ionomycin free acid

The following data is based on the product molecular weight 709.01.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.10 mL	70.52 mL	141.04 mL
0.5 mM	2.82 mL	14.10 mL	28.21 mL
1 mM	1.41 mL	7.05 mL	14.10 mL
5 mM	0.28 mL	1.41 mL	2.82 mL

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Reconstitution Calculator

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References for Ionomycin free acid

References are publications that support the biological activity of the product.

Kaufmann Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J.Biol.Chem. 1980 PMID: 6766939
Elzi Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 2001 PMID: 11401859
Liu and Hermann Characterization of ionomycin as a calcium ionophore. J.Biol.Chem. 1978 PMID: 28319