L-NAME hydrochloride

Name: L-NAME hydrochloride
Brand: Tocris Bioscience
SKU: 0665
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0665

(1)

Citations (17)

COA / SDS

Non-selective NOS inhibitor

Key Product Details

Description:	Non-selective NOS inhibitor
Chemical Name:	NG-Nitro-L-arginine methyl ester hydrochloride
Molecular Weight:	269.69

View Full Technical Details for L-NAME hydrochloride

Technical Data
Citations / Reviews (1)

Biological Activity for L-NAME hydrochloride

L-NAME hydrochloride is a NO synthase inhibitor.

Compound Libraries for L-NAME hydrochloride

L-NAME hydrochloride is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for L-NAME hydrochloride

M. Wt	269.69
Formula	C₇H₁₅N₅O₄.HCl
Storage	Store at RT
CAS Number	51298-62-5
PubChem ID	135193
InChi Key	QBNXAGZYLSRPJK-JEDNCBNOSA-N
Smiles	N=C(NCCC[C@H](N)C(OC)=O)N[N+]([O-])=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for L-NAME hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	26.97	100
	DMSO	26.97	100

Preparing Stock Solutions for L-NAME hydrochloride

The following data is based on the product molecular weight 269.69.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.71 mL	18.54 mL	37.08 mL
5 mM	0.74 mL	3.71 mL	7.42 mL
10 mM	0.37 mL	1.85 mL	3.71 mL
50 mM	0.07 mL	0.37 mL	0.74 mL

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Reconstitution Calculator

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References for L-NAME hydrochloride

References are publications that support the biological activity of the product.

Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
Pfeiffer Inhibition of nitric oxide synthesis by N^G-nitro-L-arginine methyl ester (L-NAME): requirement for bioactivation to the free acid, N^G-nitro-L-arginine. Br.J.Pharmacol. 1996 PMID: 8832069
Knowles Nitric oxide synthases in mammals. Biochem.J. 1994 PMID: 7510950