L-(-)-threo-3-Hydroxyaspartic acid

Biological Activity for L-(-)-threo-3-Hydroxyaspartic acid

Technical Data for L-(-)-threo-3-Hydroxyaspartic acid

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for L-(-)-threo-3-Hydroxyaspartic acid

References for L-(-)-threo-3-Hydroxyaspartic acid

References are publications that support the biological activity of the product.

• Johnston et al. Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate. J.Neurochem., 1980;34:241 PMID: 7452241
• McBean and Roberts Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J.Neurochem., 1985;44:247 PMID: 2856883
• Nakamura et al. (2S,3S,4R)-2-(Carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate. Neuropharmacology, 1993;32:833 PMID: 7901789
• Jensen and Bräuner-Osborne et al. Pharmacological characterization of human excitatory amino acid transporters EAAT1, EAAT2 and EAAT3 in a fluorescence-based membrane potential assay. Biochem.Pharmacol., 2004;67:2115 PMID: 15135308