Lamotrigine isethionate

Name: Lamotrigine isethionate
Brand: Tocris Bioscience
SKU: 2289

Tocris Bioscience, part of Bio-Techne | Catalog # 2289

Citations (6)

COA / SDS

Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)

Key Product Details

Chemical Name:	6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate
Purity:	≥99%
Molecular Weight:	382.22 kDa

View Full Technical Details for Lamotrigine isethionate

Technical Data
Citations

Biological Activity for Lamotrigine isethionate

Lamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na⁺, K⁺ and Ca²⁺ currents.

Technical Data for Lamotrigine isethionate

M. Wt	382.22 kDa
Formula	C₉H₇Cl₂N₅.C₂H₆O₄S
Storage	Desiccate at RT
Purity	≥99%
CAS Number	113170-86-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Lamotrigine isethionate

Solubility

Soluble Soluble to 100 mM in water with gentle warming

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References for Lamotrigine isethionate

References are publications that support the biological activity of the product.

Zona and Avoli Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture. Epilepsia, 1997;38:522 PMID: 9184596
Smith and Meldrum Cardioprotective effect of lamotr. after focal ischemia in rats. Stroke, 1995;26:117 PMID: 7839380
Grunze et al. Modulation of calcium and potassium currents by lamotr. Neuropsychobiology, 1998;38:131 PMID: 9778600
Leach et al. Neurochemical and behavioral aspects of lamotr. Epilepsia, 1991;32:S4 PMID: 1685439