Lisuride maleate

Name: Lisuride maleate
Brand: Tocris Bioscience
SKU: 4052

Tocris Bioscience, part of Bio-Techne | Catalog # 4052

Citations (9)

COA / SDS

Dopamine agonist; antiparkinson's agent

Key Product Details

Chemical Name:	N'-[(8α)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylurea maleate
Purity:	≥99%
Molecular Weight:	454.52 kDa

View Full Technical Details for Lisuride maleate

Technical Data
Citations

Biological Activity for Lisuride maleate

Lisuride maleate is a dopamine receptor agonist and anti-Parkinson's agent. Displays high affinity for D₂, D₃ and D₄ receptors along with 5-HT_1A. Exhibits some 5-HT_2B receptor antagonist properties. Decreases prolactin release; reduces inflammatory mediators such as TNF-α and IL6. Exhibits anticonvulsive effects. Acts similar to bromocriptine (Cat. No. 0427).

Technical Data for Lisuride maleate

M. Wt	454.52 kDa
Formula	C₂₀H₂₆N₄O.C₄H₄O₄
Storage	Store at RT
Purity	≥99%
CAS Number	19875-60-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Lisuride maleate

Solubility

Soluble Soluble to 100 mM in DMSO

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References for Lisuride maleate

References are publications that support the biological activity of the product.

Zweckberger et al. Anticonvulsive effects of the DA agonist lisuride maleate after experimental traumatic brain injury. Neurosci.Lett., 2010;470:150 PMID: 20056133
Woitalla et al. Transdermal lisuride delivery in the treatment of Parkinson's disease. J.Neural Transm., 2004;68:89
Hofmann et al. Lisuride, a DA receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis Clin.Neuropharmacol., 2006;29:80 PMID: 16614540