Luzindole

Name: Luzindole
Brand: Tocris Bioscience
SKU: 0877
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0877

(1)

Citations (62)

COA / SDS

Competitive melatonin MT1/MT2 antagonist

Key Product Details

Description:	Competitive melatonin MT₁/MT₂ antagonist
Chemical Name:	N-Acetyl-2-benzyltryptamine
Purity:	≥98% (HPLC)
Molecular Weight:	292.38

View Full Technical Details for Luzindole

Technical Data
Citations / Reviews (1)

Biological Activity for Luzindole

Luzindole is a melatonin antagonist.

Technical Data for Luzindole

M. Wt	292.38
Formula	C₁₉H₂₀N₂O
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	117946-91-5
PubChem ID	122162
InChi Key	WVVXBPKOIZGVNS-UHFFFAOYSA-N
Smiles	CC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Luzindole

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	29.24	100
	ethanol	29.24	100

Preparing Stock Solutions for Luzindole

The following data is based on the product molecular weight 292.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.42 mL	17.10 mL	34.20 mL
5 mM	0.68 mL	3.42 mL	6.84 mL
10 mM	0.34 mL	1.71 mL	3.42 mL
50 mM	0.07 mL	0.34 mL	0.68 mL

Molarity Calculator

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Reconstitution Calculator

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References for Luzindole

References are publications that support the biological activity of the product.

Dubocovich Anti-depressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in mouse behavioural despair test. Eur.J.Pharmacol. 1990 PMID: 2168835
Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
Dubocovich Luzindole (N-0774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2843633