Lys-[Des-Arg⁹]Bradykinin

Name: Lys-[Des-Arg 9 ]Bradykinin
Brand: Tocris Bioscience
SKU: 3225
Rating: 4 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 3225

(1)

Citations (7)

COA / SDS

Selective B1 agonist

Discontinued Product

3225 has been discontinued. View all Bradykinin Receptor Agonists products.

Key Product Details

Description:	Selective B₁ agonist
Alternative Names:	Des-Arg¹⁰-Kallidin
Purity:	≥95% (HPLC)
Molecular Weight:	1032.21

View Full Technical Details for Lys-[Des-Arg⁹]Bradykinin

Technical Data
Citations / Reviews (1)

Biological Activity for Lys-[Des-Arg⁹]Bradykinin

Lys-[Des-Arg⁹]Bradykinin is an endogenous potent and highly selective bradykinin B₁ receptor agonist (K_i values are 0.12 and > 30000 nM at human B₁ and B₂ receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin (Cat No. 3005).

Technical Data for Lys-[Des-Arg⁹]Bradykinin

M. Wt	1032.21
Formula	C₅₀H₇₃N₁₃O₁₁
Single Letter Sequence	KRPPGFSPF
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	71800-36-7
PubChem ID	122227
InChi Key	AILVBOHFGXNHCC-TZPCGENMSA-N
Smiles	[H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Lys-[Des-Arg⁹]Bradykinin

References are publications that support the biological activity of the product.

Regoli Classification of kinin receptors. Biol.Chem. 2001 PMID: 11258668
Leeb-Lundberg International union of pharmacology. LV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 2005 PMID: 15734727
Drapeau Hypotensive effects of Lys-des-Arg⁹-Bradykinin and metabolically protected agonists of B₁ receptors for kinins. J.Pharmacol.Exp.Ther. 1991 PMID: 1662280

Lys-[Des-Arg⁹]Bradykinin

Tocris Bioscience, part of Bio-Techne | Catalog # 3225

Key Product Details

Biological Activity for Lys-[Des-Arg⁹]Bradykinin

Technical Data for Lys-[Des-Arg⁹]Bradykinin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Lys-[Des-Arg⁹]Bradykinin

Product Documents for Lys-[Des-Arg⁹]Bradykinin

COA

Certificate of Analysis

SDS

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Lys-[Des-Arg9]Bradykinin

Tocris Bioscience, part of Bio-Techne | Catalog # 3225

Key Product Details

Biological Activity for Lys-[Des-Arg9]Bradykinin

Technical Data for Lys-[Des-Arg9]Bradykinin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Lys-[Des-Arg9]Bradykinin

Product Documents for Lys-[Des-Arg9]Bradykinin

COA

Certificate of Analysis

SDS

Lys-[Des-Arg⁹]Bradykinin

Biological Activity for Lys-[Des-Arg⁹]Bradykinin

Technical Data for Lys-[Des-Arg⁹]Bradykinin

References for Lys-[Des-Arg⁹]Bradykinin

Product Documents for Lys-[Des-Arg⁹]Bradykinin