MDL 72222

Name: MDL 72222
Brand: Tocris Bioscience
SKU: 0640
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0640

(1)

Citations (27)

COA / SDS

5-HT3 antagonist

Key Product Details

Description:	5-HT₃ antagonist
Chemical Name:	Tropanyl 3,5-dichlorobenzoate
Purity:	≥99% (HPLC)
Molecular Weight:	314.21

View Full Technical Details for MDL 72222

Technical Data
Citations / Reviews (1)

Biological Activity for MDL 72222

MDL 72222 is a 5-HT₃ antagonist.

Compound Libraries for MDL 72222

MDL 72222 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for MDL 72222

M. Wt	314.21
Formula	C₁₅H₁₇Cl₂NO₂
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	40796-97-2
PubChem ID	1683
InChi Key	MNJNPLVXBISNSX-UHFFFAOYSA-N
Smiles	CN1C2CCC1CC(C2)OC(=O)C1=CC(Cl)=CC(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for MDL 72222

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO		100

Preparing Stock Solutions for MDL 72222

The following data is based on the product molecular weight 314.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.18 mL	15.91 mL	31.83 mL
5 mM	0.64 mL	3.18 mL	6.37 mL
10 mM	0.32 mL	1.59 mL	3.18 mL
50 mM	0.06 mL	0.32 mL	0.64 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for MDL 72222

References are publications that support the biological activity of the product.

Richardson and Engel The pharmacology and function of 5-HT₃ receptors. Trends Neurosci.
Fozard MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors. Naunyn Schmiedebergs Arch.Pharmacol. 1984 PMID: 6472484