Mpro 13b-H

Name: Mpro 13b-H
Brand: Tocris Bioscience
SKU: 7853

Tocris Bioscience, part of Bio-Techne | Catalog # 7853

COA / SDS

Negative control for Mpro 13b-K (Cat. No. 7228)

Key Product Details

Description:	Negative control for Mpro 13b-K (Cat. No. 7228)
Chemical Name:	tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Purity:	≥97% (HPLC)
Molecular Weight:	593.68

View Full Technical Details for Mpro 13b-H

Technical Data
Citations

Biological Activity for Mpro 13b-H

Mpro 13b-H is a negative control for the coronavirus Mpro inhibitor, Mpro 13b-K (Cat. No. 7228).

Licensing Information

Sold under license from the University of Luebeck

Technical Data for Mpro 13b-H

M. Wt	593.68
Formula	C₃₁H₃₉N₅O₇
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	3031351-76-2
InChi Key	NLVRHQFXQFSBQK-OEMFJLHTSA-N
Smiles	CC(C)(OC(NC1=CC=CN(C1=O)[C@@H](C(N[C@H](C(C(NCC2=CC=CC=C2)=O)=O)C[C@@H]3CCNC3=O)=O)CC4CC4)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Mpro 13b-H

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	11.87	20

Preparing Stock Solutions for Mpro 13b-H

The following data is based on the product molecular weight 593.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	8.42 mL	42.11 mL	84.22 mL
1 mM	1.68 mL	8.42 mL	16.84 mL
2 mM	0.84 mL	4.21 mL	8.42 mL
10 mM	0.17 mL	0.84 mL	1.68 mL

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Reconstitution Calculator

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References for Mpro 13b-H

References are publications that support the biological activity of the product.

Cooper Diastereomeric resolution yields highly potent inhibitor of SARS-CoV-2 main protease. J.Med.Chem. 2022 PMID: 36179320