Neurokinin B (human, porcine)

Name: Neurokinin B (human, porcine)
Brand: Tocris Bioscience
SKU: 1582

Tocris Bioscience, part of Bio-Techne | Catalog # 1582

Citations (3)

COA / SDS

Endogenous tachykinin peptide

Key Product Details

Description:	Endogenous tachykinin peptide
Alternative Names:	NKB
Purity:	≥95% (HPLC)
Molecular Weight:	1210.43

View Full Technical Details for Neurokinin B (human, porcine)

Technical Data
Citations

Biological Activity for Neurokinin B (human, porcine)

Neurokinin B (human, porcine) is an endogenous tachykinin agonist peptide that shows preference for the NK₃ receptor (EC₅₀ = 1 nM).

Technical Data for Neurokinin B (human, porcine)

M. Wt	1210.43
Formula	C₅₅H₇₉N₁₃O₁₄S₂
Single Letter Sequence	DMHDFFVGLM (Modifications: Met-10 = C-terminal amide)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	86933-75-7
PubChem ID	5311312
InChi Key	NHXYSAFTNPANFK-HDMCBQFHSA-N
Smiles	[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Neurokinin B (human, porcine)

Solubility

Soluble to 1mg/ml in DMSO

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References for Neurokinin B (human, porcine)

References are publications that support the biological activity of the product.

Severini The tachykinin peptide family. Pharmacol.Rev. 2002 PMID: 12037144
Wang Neurokinin B potentiates ATP-activated currents in rat DRG neurons. Brain Res. 2001 PMID: 11743983
Laufer Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin. Proc.Natl.Acad.Sci.U.S.A. 1985 PMID: 2414777