Neuromedin S (rat)

Name: Neuromedin S (rat)
Brand: Tocris Bioscience
SKU: 3648

Tocris Bioscience, part of Bio-Techne | Catalog # 3648

Citations (1)

COA / SDS

Potent, endogenous NMU1 and NMU2 agonist

Discontinued Product

3648 has been discontinued. View all Neuromedin U Receptor Agonists products.

Key Product Details

Description:	Potent, endogenous NMU₁ and NMU₂ agonist
Molecular Weight:	4241.97

View Full Technical Details for Neuromedin S (rat)

Technical Data
Citations

Biological Activity for Neuromedin S (rat)

Neuromedin S (rat) is a potent, endogenous neuromedin U receptor agonist (EC₅₀ values are 65 and 91 pM at NMU₁ and NMU₂ respectively). Induces phase shifts in the circadian rhythm of locomotor activity following i.c.v. administration. Potent endogenous anorexigenic peptide.

Technical Data for Neuromedin S (rat)

M. Wt	4241.97
Formula	C₁₉₃H₃₀₇N₅₇O₄₉S
Single Letter Sequence	LPRLLHTDSRMATIDFPKKDPTTSLGRPFFLFRPRN (Modifications: Asn-36 = C-terminal amide)
Storage	Store at -20°C
CAS Number	843782-19-4
PubChem ID	90488896
InChi Key	FJADBVUPVZKUEP-OFGSCBOVSA-N
Smiles	[H]N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Neuromedin S (rat)

References are publications that support the biological activity of the product.

Ida Neuromedin S is a novel anorexigenic hormone. Endocrinology 2005 PMID: 15976061
Mitchell Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S. Br.J.Pharmacol. 2009 PMID: 19519756
Mori Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 2005 PMID: 15635449

Neuromedin S (rat)

Tocris Bioscience, part of Bio-Techne | Catalog # 3648

Key Product Details

Biological Activity for Neuromedin S (rat)

Technical Data for Neuromedin S (rat)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Neuromedin S (rat)

Product Documents for Neuromedin S (rat)

COA

Certificate of Analysis

SDS

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