NSC 23005 sodium

Name: NSC 23005 sodium
Brand: Tocris Bioscience
SKU: 5779

Tocris Bioscience, part of Bio-Techne | Catalog # 5779

COA / SDS

Potently promotes HSC expansion ; p18INK inhibitor

Discontinued Product

5779 has been discontinued. View all Compounds for HSC Proliferation and Renewal products.

Key Product Details

Description:	Potently promotes HSC expansion ; p18^INK inhibitor
Chemical Name:	4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt
Purity:	≥99% (HPLC)
Molecular Weight:	305.33

View Full Technical Details for NSC 23005 sodium

Technical Data
Citations

Biological Activity for NSC 23005 sodium

NSC 23005 sodium is a p18^INK inhibitor. Potently promotes hematopoietic stem cell (HSC) expansion (ED₅₀ = 5.21 nM). Exhibits no effect on leukemia cell proliferation.

Compound Libraries for NSC 23005 sodium

NSC 23005 sodium is also offered as part of the Tocriscreen Stem Cell Library. Find out more about compound libraries available from Tocris.

Technical Data for NSC 23005 sodium

M. Wt	305.33
Formula	C₁₃H₁₆NNaO₄S
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	1796596-46-7
PubChem ID	122705986
InChi Key	MLHFBDVMTRIQMW-UHFFFAOYSA-M
Smiles	O=S(C1=CC=C(C([O-])=O)C=C1)(NC2CCCCC2)=O.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NSC 23005 sodium

References are publications that support the biological activity of the product.

Xie Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci.Rep. 2015 PMID: 26681454