NSC 87877

Biological Activity for NSC 87877

Technical Data for NSC 87877

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for NSC 87877

References for NSC 87877

References are publications that support the biological activity of the product.

• Kim S, Cho Y, Kim H, Oh J, Ahn E, Ko H, Hwang B, Lee S, Cho Y, Kim Y, Stetler-Stevenson W, Seo D Antagonism of VEGF-A-induced increase in vascular permeability by an integrin alpha3beta1-Shp-1-cAMP/PKA pathway. Blood, 2012;120(24):4892-902. 2012 PMID: 23074279
• FH Brennan, T Jogia, ER Gillespie, LV Blomster, XX Li, B Nowlan, GM Williams, E Jacobson, GW Osborne, FA Meunier, SM Taylor, KE Campbell, KP MacDonald, JP Levesque, TM Woodruff, MJ Ruitenberg Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2 JCI Insight, 2019;4(9):. 2019 PMID: 31045582
• Fraineau S, Monvoisin A, Clarhaut J, Talbot J, Simonneau C, Kanthou C, Kanse S, Philippe M, Benzakour O The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner. Blood, 2012;120(25):5073-83. 2012 PMID: 23065156
• Soong, Joanne, Scott, Glynis Plexin B1 inhibits MET through direct association and regulates Shp2 expression in melanocytes. J Cell Sci, 0;126(0):688-95. 0 PMID: 23203808
• Chen et al. Discovery of a novel shp2 protein tyrosine phosphatase inhibitor. Mol.Pharmacol., 2006;70:562 PMID: 16717135
• Zhao et al. Regulation of ACh receptor clustering by the tyrosine phosphatase Shp2. Dev.Neurobiol., 2007;67:1789 PMID: 17659592
• Redonde et al. hTRPC1-associated α-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation. J.Thromb.Haemost., 2007;5:2476 PMID: 17892531