PP 1

Biological Activity for PP 1

Technical Data for PP 1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PP 1

References for PP 1

References are publications that support the biological activity of the product.

• Bain et al. The specificities of protein kinase inhibitors: an update. Biochem.J., 2003;371:199 PMID: 12534346
• Carlomagno et al. The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes. Cancer Res., 2002;62:1077 PMID: 11861385
• Hanke et al. Discovery of a novel, potent, and src family-selective tyrosine kinase inhibitor. J.Biol.Chem., 1996;271:695 PMID: 8557675
• Liu et al. Structural basis for selective inhibition of Src family kinases by PP1. Chem.Biol., 1999;6:671 PMID: 10467133
• Tatton et al. The src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases. J.Biol.Chem., 2003;278:4847 PMID: 12475982