PPNDS

Name: PPNDS
Brand: Tocris Bioscience
SKU: 1309

Tocris Bioscience, part of Bio-Techne | Catalog # 1309

Citations (7)

COA / SDS

Potent and selective P2X1 antagonist

Discontinued Product

1309 has been discontinued. View all P2X Receptor Antagonists products.

Key Product Details

Description:	Potent and selective P2X₁ antagonist
Chemical Name:	Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt
Molecular Weight:	694.36

View Full Technical Details for PPNDS

Technical Data
Citations

Biological Activity for PPNDS

PPNDS is a potent and selective P2X₁ receptor antagonist (pK_B = 7.43 in rat vas deferens). Up to 52-fold selective over P2Y₁ receptors, and selective over ecto-nucleotidase, α_1A-adrenoceptors, A₁, A_2B, H₁ and M₃ receptors.

Technical Data for PPNDS

M. Wt	694.36
Formula	C₁₈H₁₁N₄Na₄O₁₄PS₂
Storage	Desiccate at -20°C
CAS Number	1021868-77-8
PubChem ID	2750
InChi Key	XHWIRFKQZFSILU-MKMLRUMESA-J
Smiles	CC1=C(O)C(C=O)=C(COP(O[Na])(O[Na])=O)C(/N=N/C2=CC3=C(C=C(C=C3C(S(=O)(O[Na])=O)=C2)[N+]([O-])=O)S(=O)(O[Na])=O)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for PPNDS

References are publications that support the biological activity of the product.

Lambrecht The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X₁ receptors. Eur.J.Pharmacol. 2000 PMID: 10650184

PPNDS

Tocris Bioscience, part of Bio-Techne | Catalog # 1309

Key Product Details

Biological Activity for PPNDS

Technical Data for PPNDS

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for PPNDS

Product Documents for PPNDS

COA

Certificate of Analysis

SDS

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