P2X Receptor Antagonists: Small Molecules and Peptides
ATP-gated ion channels, P2X purinergic receptors are composed of three subunits. They confer specific receptor subtype pharmacology and are permeable to cations.
23 results for "P2X Receptor Antagonists Small Molecules and Peptides" in Products
23 results for "P2X Receptor Antagonists Small Molecules and Peptides" in Products
P2X Receptor Antagonists: Small Molecules and Peptides
ATP-gated ion channels, P2X purinergic receptors are composed of three subunits. They confer specific receptor subtype pharmacology and are permeable to cations.
Non-selective P2 antagonist
| Chemical Name: | Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid tetrasodium salt |
Competitive P2X7 antagonist
| Chemical Name: | 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride |
| Purity: | ≥98% |
Non-competitive P2X7 antagonist
| Chemical Name: | 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester |
| Purity: | ≥98% (HPLC) |
Highly selective P2X1 antagonist
| Chemical Name: | 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt |
| Purity: | ≥90% (HPLC) |
Potent and selective P2X7 antagonist
| Chemical Name: | N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide |
| Purity: | ≥97% |
Potent and selective P2X4 antagonist
| Chemical Name: | 5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one |
| Purity: | ≥99% |
Non-selective P2X antagonist
| Chemical Name: | Pyridoxalphosphate-6-azophenyl-2',5'-disulfonic acid tetrasodium salt |
Potent P2X7 antagonist
| Chemical Name: | N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective P2X antagonist
| Chemical Name: | 2',3'-O-(2,4,6-Trinitrophenyl)adenosine-5'-triphosphate tetra(triethylammonium) salt |
| Purity: | ≥95% |
Potent and selective P2X7 antagonist
| Chemical Name: | N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine |
| Purity: | ≥99% (HPLC) |
Non-selective P2 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥98% (HPLC) |
Selective P2Y11 and P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥90% |
Potent P2X3 and P2X2/3 antagonist
| Chemical Name: | 2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinyl]amino]-1,3-propanediol |
| Purity: | ≥98% (HPLC) |
Selective and competitive P2X1 antagonist
| Chemical Name: | 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid, hexasodium salt |
Selective P2X4 allosteric antagonist
| Chemical Name: | N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea |
| Purity: | ≥99% (HPLC) |
Potent and selective P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥95% (HPLC) |
Potent and selective human P2X7 antagonist
| Chemical Name: | 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl)oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidinedione |
| Purity: | ≥98% (HPLC) |
Potent and selective P2X7 antagonist; brain penetrant
| Chemical Name: | 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide |
| Purity: | ≥98% |
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
| Chemical Name: | 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt |
| Purity: | ≥90% (HPLC) |
Selective P2X3 and P2X2/3 antagonist
| Chemical Name: | 5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
| Chemical Name: | 5-[[[(3-Phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt |
| Purity: | ≥98% |
Potent P2X3 antagonist
| Chemical Name: | 4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonic acid tetrasodium salt |
| Purity: | ≥90% (HPLC) |
Selective P2X4 antagonist
| Chemical Name: | N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide |
| Purity: | ≥98% |
