Prostaglandin E₂

Biological Activity for Prostaglandin E₂

Technical Data for Prostaglandin E₂

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Prostaglandin E₂

References for Prostaglandin E₂

References are publications that support the biological activity of the product.

• H Gassmann, K Schneider, V Evdokimova, P Ruzanov, SJ Schober, B Xue, K von Heykin, M Thiede, GHS Richter, MW Pfaffl, E Noessner, LD Stein, PH Sorensen, SEG Burdach, U Thiel Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function Cells, 2021;10(8):. 2021 PMID: 34440851
• A Gutjahr, L Papagno, F Vernejoul, T Lioux, F Jospin, B Chanut, E Perouzel, N Rochereau, V Appay, B Verrier, S Paul New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses EBioMedicine, 2020;58(0):102922. 2020 PMID: 32739871
• KH Nilsson, P Henning, ME Shahawy, M Nethander, TL Andersen, C Ejersted, J Wu, KL Gustafsson, A Koskela, J Tuukkanen, PPC Souza, J Tuckermann, M Lorentzon, LE Ruud, T Lehtimäki, JH Tobias, S Zhou, UH Lerner, JB Richards, S Movérare-S, C Ohlsson RSPO3 is important for trabecular bone and fracture risk in mice and humans Nature Communications, 2021;12(1):4923. 2021 PMID: 34389713
• L Puca, R Bareja, D Prandi, R Shaw, M Benelli, WR Karthaus, J Hess, M Sigouros, A Donoghue, M Kossai, D Gao, J Cyrta, V Sailer, A Vosoughi, C Pauli, Y Churakova, C Cheung, LD Deonarine, TJ McNary, R Rosati, ST Tagawa, DM Nanus, JM Mosquera, CL Sawyers, Y Chen, G Inghirami, RA Rao, C Grandori, O Elemento, A Sboner, F Demichelis, MA Rubin, H Beltran Patient derived organoids to model rare prostate cancer phenotypes Nat Commun, 2018;9(1):2404. 2018 PMID: 29921838
• Aldi S, Robador P, Tomita K, Di Lorenzo A, Levi R IgE receptor-mediated mast-cell renin release. Am J Pathol, 2014;184(2):376-81. 2014 PMID: 24262755
• L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis Autophagy, 2017;0(0):0. 2017 PMID: 28933598
• LC Dutton, J Dudhia, B Catchpole, H Hodgkiss-G, D Werling, DJ Connolly Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor Sci Rep, 2018;8(1):13351. 2018 PMID: 30190508
• SJ Hill, B Decker, EA Roberts, NS Horowitz, MG Muto, MJ Worley, CM Feltmate, MR Nucci, EM Swisher, H Nguyen, C Yang, R Morizane, BS Kochupurak, KT Do, PA Konstantin, JF Liu, JV Bonventre, UA Matulonis, GI Shapiro, RS Berkowitz, CP Crum, AD D'Andrea Prediction of DNA Repair Inhibitor Response in Short Term Patient-Derived Ovarian Cancer Organoids Cancer Discov, 2018;0(0):. 2018 PMID: 30213835
• Coleman et al. Classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol.Rev., 1994;46:205 PMID: 7938166
• North et al. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature., 2007;447:1007 PMID: 17581586
• Hata and Breyer Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharm.Ther., 2004;103:147
• Karthaus et al. Identification of multipotent luminal progenitor cells in human prostate organoid cultures. Cell, 2014;159:163 PMID: 25201529
• Sato et al. SnapShot: Growing Organoids from Stem Cells. Cell, 2015;161:1700 PMID: 26091044
• Heffner et al. Prostaglandin E₂ increases lentiviral vector transduction efficiency of adult human hematopoietic stem and progenitor cells. Mol.Ther, 2018;26:320 PMID: 29102562