RepSox

Biological Activity for RepSox

Technical Data for RepSox

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for RepSox

References for RepSox

References are publications that support the biological activity of the product.

• Zhou A, Kozhaya L, Fujii H, Unutmaz D GARP-TGF-beta complexes negatively regulate regulatory T cell development and maintenance of peripheral CD4+ T cells in vivo. J Immunol, 2013;190(10):5057-64. 2013 PMID: 23576681
• TM Triolo, JQ Matuschek, R Castro-Gut, AH Shilleh, SPM Williams, MS Hansen, K McDaniel, JM Barra, A Michels, HA Russ Stem-Cell-Derived beta-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity Cells, 2022;11(23):. 2022 PMID: 36497105
• Zhou A, El Hed A, Mercer F, Kozhaya L, Unutmaz D The metalloprotease ADAM12 regulates the effector function of human Th17 cells. PLoS ONE, 2013;8(11):e81146. 2013 PMID: 24363794
• KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, S Mejia-Guer, Y Aghazadeh, JL Rourke, RA Screaton, M Grompe, PR Streeter, AC Powers, M Brissova, T Kislinger, MC Nostro Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors Nat Commun, 2017;8(1):331. 2017 PMID: 28835709
• Gellibert et al. Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-γ type I receptor inhibitors. J.Med.Chem., 2004;47:4494 PMID: 15317461
• Li et al. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell, 2009;4:16 PMID: 19097958
• Ichida et al. A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell, 2009;5:491 PMID: 19818703