Reserpine

Name: Reserpine
Brand: Tocris Bioscience
SKU: 2742
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2742

(1)

Citations (24)

COA / SDS

Inhibitor of vesicular monoamine transport

Key Product Details

Description:	Inhibitor of vesicular monoamine transport
Chemical Name:	(3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
Purity:	≥99% (HPLC)
Molecular Weight:	608.68

View Full Technical Details for Reserpine

Technical Data
Citations / Reviews (1)

Biological Activity for Reserpine

Binds the vesicular monoamine transporter (VMAT2) and inhibits transport of biogenic amines into adrenal chromaffin granules and synaptic vesicles. Causes depletion of biogenic amine stores. Antihypertensive and antipsychotic.

Technical Data for Reserpine

M. Wt	608.68
Formula	C₃₃H₄₀N₂O₉
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	50-55-5
PubChem ID	5770
InChi Key	QEVHRUUCFGRFIF-MDEJGZGSSA-N
Smiles	[H][C@@](N4CC3)(C[C@@]([C@H]([C@@](OC)=O)[C@@H](OC)[C@H](OC(C6=CC(OC)=C(OC)C(OC)=C6)=O)C5)([H])[C@@]5([H])C4)C2=C3C1=C(N2)C=C(OC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Reserpine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	6.09	10

Preparing Stock Solutions for Reserpine

The following data is based on the product molecular weight 608.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.43 mL	82.14 mL	164.29 mL
0.5 mM	3.29 mL	16.43 mL	32.86 mL
1 mM	1.64 mL	8.21 mL	16.43 mL
5 mM	0.33 mL	1.64 mL	3.29 mL

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References for Reserpine

References are publications that support the biological activity of the product.

Heslop and Curzon Effect of rese. on behavioural responses to agonists at 5-HT_1A, 5-HT_1B, 5-HT_2A, and 5-HT_2C receptor subtypes. Neuropharmacology 1999 PMID: 10465692
Metzger Inhibitory effect of rese. on DA transporter function. Eur.J.Pharmacol. 2002 PMID: 12450567
Schuldiner Reserpine binding to a vesicular amine transporter expressed in chinese hamster ovary fibroblasts. J.Biol.Chem. 1993 PMID: 8416935

Product Documents for Reserpine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Reserpine, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov