(RS)-(±)-Sulpiride

Name: ( RS )-(±)-Sulpiride
Brand: Tocris Bioscience
SKU: 0894
Rating: 4 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0894

(2)

Citations (10)

COA / SDS

Standard selective D2-like antagonist

Key Product Details

Description:	Standard selective D₂-like antagonist
Chemical Name:	(RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
Purity:	≥98% (HPLC)
Molecular Weight:	341.42

View Full Technical Details for (RS)-(±)-Sulpiride

Technical Data
Citations / Reviews (2)

Biological Activity for (RS)-(±)-Sulpiride

(RS)-(±)-Sulpiride is a standard D₂-like dopamine receptor antagonist.

S-enantiomer also available.

Compound Libraries for (RS)-(±)-Sulpiride

(RS)-(±)-Sulpiride is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for (RS)-(±)-Sulpiride

M. Wt	341.42
Formula	C₁₅H₂₃N₃O₄S
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	15676-16-1
PubChem ID	5355
InChi Key	BGRJTUBHPOOWDU-UHFFFAOYSA-N
Smiles	CCN1CCCC1CNC(=O)C1=C(OC)C=CC(=C1)S(N)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (RS)-(±)-Sulpiride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	34.14	100

Preparing Stock Solutions for (RS)-(±)-Sulpiride

The following data is based on the product molecular weight 341.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.93 mL	14.64 mL	29.29 mL
5 mM	0.59 mL	2.93 mL	5.86 mL
10 mM	0.29 mL	1.46 mL	2.93 mL
50 mM	0.06 mL	0.29 mL	0.59 mL

Molarity Calculator

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Reconstitution Calculator

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References for (RS)-(±)-Sulpiride

References are publications that support the biological activity of the product.

Seeman and Van Tol DA receptor pharmacology. TiPS 1994 PMID: 7940991
Seeman and Van Tol DA D₄ receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective. Eur.J.Pharmacol. 1993 PMID: 8097160