RuBi-GABA

Name: RuBi-GABA
Brand: Tocris Bioscience
SKU: 3400

Tocris Bioscience, part of Bio-Techne | Catalog # 3400

Citations (35)

COA / SDS

Caged GABA; excitable at visible wavelengths

Key Product Details

Description:	Caged GABA; excitable at visible wavelengths
Chemical Name:	(bis(2,2'-Bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex
Molecular Weight:	922.8

View Full Technical Details for RuBi-GABA

Technical Data
Citations

Biological Activity for RuBi-GABA

RuBi-GABA is a ruthenium-bipyridine-triphenylphosphine caged GABA (Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.

Licensing Information

Sold under licence from Columbia University

Technical Data for RuBi-GABA

M. Wt	922.8
Formula	C₄₂H₃₉F₆N₅O₂P₂Ru
Storage	Store at -20°C
CAS Number	1028141-88-9
PubChem ID	117071637
InChi Key	YMUDUHPMAODLNP-UHFFFAOYSA-N
Smiles	[Ru++].NCCCC([O-])=O.F[P-](F)(F)(F)(F)F.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1.C1=CC=C(C=C1)P(C1=CC=CC=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for RuBi-GABA

References are publications that support the biological activity of the product.

Rial Verde Photorelease of GABA with visible light using an inorganic caging group. Front.Neural Circuits 2008 PMID: 18946542
Zayat A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 2003 PMID: 12537482