RuBi-GABA

Name: RuBi-GABA
Brand: Tocris Bioscience
SKU: 3400

Tocris Bioscience, part of Bio-Techne | Catalog # 3400

Citations (35)

COA / SDS

Caged GABA; excitable at visible wavelengths

Key Product Details

Chemical Name:	(bis(2,2'-Bipyridine-N,N')triphenylphosphine)-4-aminobutyric acid ruthenium hexafluorophosphate complex
Molecular Weight:	922.8 kDa

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Technical Data
Citations

Biological Activity for RuBi-GABA

RuBi-GABA is a ruthenium-bipyridine-triphenylphosphine caged GABA (Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.

Technical Data for RuBi-GABA

M. Wt	922.8 kDa
Formula	C₄₂H₃₉F₆N₅O₂P₂Ru
Storage	Store at -20°C
CAS Number	1028141-88-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for RuBi-GABA

References are publications that support the biological activity of the product.

Zayat et al. A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc., 2003;125:882 PMID: 12537482
Rial Verde et al. Photorelease of GABA with visible light using an inorganic caging group. Front.Neural Circuits, 2008;2:2 PMID: 18946542

RuBi-GABA

Tocris Bioscience, part of Bio-Techne | Catalog # 3400

Key Product Details

Biological Activity for RuBi-GABA

Technical Data for RuBi-GABA

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for RuBi-GABA

Product Documents for RuBi-GABA

COA

Certificate of Analysis

SDS

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