RuBi-Glutamate

Name: RuBi-Glutamate
Brand: Tocris Bioscience
SKU: 3574

Tocris Bioscience, part of Bio-Techne | Catalog # 3574

(1)

Citations (23)

COA / SDS

Caged glutamate; excited by visible wavelengths

Key Product Details

Chemical Name:	(bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2⁺) complex sodium hexafluorophosphate salt
Molecular Weight:	970.54 kDa

View Full Technical Details for RuBi-Glutamate

Technical Data
Citations / Reviews (1)

Biological Activity for RuBi-Glutamate

RuBi-Glutamate is a ruthenium-bipyridine-trimethylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Displays high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.

MNI-caged-L-glutamate (Cat. No. 1490) also available.

Technical Data for RuBi-Glutamate

M. Wt	970.54 kDa
Formula	C₂₈H₃₂N₅O₄PRu.2NaPF₆
Storage	Store at -20°C
CAS Number	2417096-44-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for RuBi-Glutamate

Solubility

Soluble Soluble to 20 mM in water

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References for RuBi-Glutamate

References are publications that support the biological activity of the product.

Fino et al. RuBi-Glutamate: two-photon and visible-light photoactivation of neurons and dendritic spines. Front.Neural Circuits, 2009;3:1 PMID: 19506708
Salierno et al. A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes. J.Inorg.Biochem., 2010;104:418 PMID: 20060592