SA 57

Name: SA 57
Brand: Tocris Bioscience
SKU: 4752

Tocris Bioscience, part of Bio-Techne | Catalog # 4752

COA / SDS

Potent FAAH inhibitor

Discontinued Product

4752 has been discontinued. View all Fatty Acid Amide Hydrolase (FAAH) Inhibitors products.

Key Product Details

Description:	Potent FAAH inhibitor
Chemical Name:	4-[2-(4-Chlorophenyl)ethyl]-1-piperidinecarboxylic acid 2-(methylamino)-2-oxoethyl ester
Purity:	≥99% (HPLC)
Molecular Weight:	338.83

View Full Technical Details for SA 57

Technical Data
Citations

Biological Activity for SA 57

SA 57 is a potent inhibitor of fatty acid amide hydrolase (FAAH) (IC₅₀ <10 nM). Also inhibits MAGL at higher concentrations (IC₅₀ values are 410 nM and 1.4 μM respectively). Inhibits both human and mouse FAAH enzymes. Exhibits inhibitory activity against FAAH, MAGL and ABHD6 in vivo.

Technical Data for SA 57

M. Wt	338.83
Formula	C₁₇H₂₃ClN₂O₃
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	1346169-63-8
PubChem ID	44589122
InChi Key	JFSSVCSHPDLFCM-UHFFFAOYSA-N
Smiles	ClC(C=C2)=CC=C2CCC1CCN(C(OCC(NC)=O)=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for SA 57

References are publications that support the biological activity of the product.

Owens Discriminative stimulus properties of the endocannabinoid catabolic enzyme inhibitor SA-57 in mice. J.Pharmacol.Exp.Ther 2016 PMID: 27307500
Niphakis O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors. ACS Chem.Neurosci. 2012 PMID: 22860211

SA 57

Tocris Bioscience, part of Bio-Techne | Catalog # 4752

Key Product Details

Biological Activity for SA 57

Technical Data for SA 57

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for SA 57

Product Documents for SA 57

COA

Certificate of Analysis

SDS

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