Spermine tetrahydrochloride

Name: Spermine tetrahydrochloride
Brand: Tocris Bioscience
SKU: 0958

Tocris Bioscience, part of Bio-Techne | Catalog # 0958

Citations (27)

COA / SDS

Modulator at polyamine site

Key Product Details

Chemical Name:	N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
Molecular Weight:	348.19 kDa

View Full Technical Details for Spermine tetrahydrochloride

Technical Data
Citations

Biological Activity for Spermine tetrahydrochloride

Spermine tetrahydrochloride is a polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.

Technical Data for Spermine tetrahydrochloride

M. Wt	348.19 kDa
Formula	C₁₀H₂₆N₄.4HCl
Storage	Desiccate at +4°C
CAS Number	306-67-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Spermine tetrahydrochloride

Solubility

Soluble Soluble to 100 mM in water

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References for Spermine tetrahydrochloride

References are publications that support the biological activity of the product.

Benveniste and Mayer Multiple effects of spermine on N-MthD.-aspartic acid receptor responses of rat cultured hippocampal neurones. J.Physiol., 1993;464:131 PMID: 8229795
Doyle and Shaw Investigation of the actions and antagonist activity of some polyamine analogues in vivo. Br.J.Pharmacol., 1998;124:386 PMID: 9641557
Johnson Modulation of channel function by polyamines. TiPS, 1996;17:22 PMID: 8789355
Munir et al. Polyamines modulate the neurotoxic effects of NMDA in vivo. Brain Res., 1993;616:163 PMID: 8358608