SSM 3 trifluoroacetate

Name: SSM 3 trifluoroacetate
Brand: Tocris Bioscience
SKU: 5253

Tocris Bioscience, part of Bio-Techne | Catalog # 5253

Citations (1)

COA / SDS

Potent furin inhibitor

Key Product Details

Description:	Potent furin inhibitor
Chemical Name:	rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt
Purity:	≥98% (HPLC)
Molecular Weight:	952.66

View Full Technical Details for SSM 3 trifluoroacetate

Technical Data
Citations

Biological Activity for SSM 3 trifluoroacetate

SSM 3 trifluoroacetate is a potent furin inhibitor (EC₅₀ = 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro.

Compound Libraries for SSM 3 trifluoroacetate

SSM 3 trifluoroacetate is also offered as part of the Tocriscreen Antiviral Library. Find out more about compound libraries available from Tocris.

Technical Data for SSM 3 trifluoroacetate

M. Wt	952.66
Formula	C₂₂H₃₂N₁₂O₂.4CF₃CO₂H
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2320930-10-5
PubChem ID	121513857
InChi Key	JYRRXGHBFAELIV-YAOLEPIASA-N
Smiles	NC(N[C@H]1C[C@@H](NC(N)=N)[C@H](OC3=CC=C(NC(N)=N)C=C3)C[C@@H]1OC2=CC=C(NC(N)=N)C=C2)=N.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SSM 3 trifluoroacetate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	49.66	100
	DMSO	49.66	100

Preparing Stock Solutions for SSM 3 trifluoroacetate

The following data is based on the product molecular weight 952.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.05 mL	5.25 mL	10.50 mL
5 mM	0.21 mL	1.05 mL	2.10 mL
10 mM	0.10 mL	0.52 mL	1.05 mL
50 mM	0.02 mL	0.10 mL	0.21 mL

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Reconstitution Calculator

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References for SSM 3 trifluoroacetate

References are publications that support the biological activity of the product.

Remacle Selective and potent furin inhibitors protect cells from anthrax without significant toxicity. Int.J.Biochem.Cell Biol. 2010 PMID: 20197107