SU 6656

Name: SU 6656
Brand: Tocris Bioscience
SKU: 6475

Tocris Bioscience, part of Bio-Techne | Catalog # 6475

Citations (27)

COA / SDS

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

Key Product Details

Chemical Name:	2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide
Purity:	≥98%

View Full Technical Details for SU 6656

Technical Data
Citations

Biological Activity for SU 6656

SU 6656 is a potent ATP-competitive Src family kinase inhibitor (IC₅₀ values are 0.02, 0.13, 0.17, 0.28 and 6.88 nM for Yes, Lyn, Fyn, Src and Lck, respectively). Exhibits > 6.5 fold selectivity for Src family over other kinases. Also AMPK inhibitor (IC₅₀ = 0.22 μM for the α2 kinase domain). Cell permeable.

Technical Data for SU 6656

Formula	C₁₉H₂₁N₃O₃S
Storage	Store at -20°C
Purity	≥98%
CAS Number	330161-87-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SU 6656

Solubility

Soluble Soluble to 100 mM in DMSO

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References for SU 6656

References are publications that support the biological activity of the product.

Blake et al. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol.Cell Biol., 2000;20:9018 PMID: 11074000
Ross et al. Mechanisms of paradoxical activation of AMPK by the kinase inhibitors SU6656 and sora. Cell.Chem.Biol., 2017;24:813 PMID: 28625738

SU 6656

Tocris Bioscience, part of Bio-Techne | Catalog # 6475

Key Product Details

Biological Activity for SU 6656

Technical Data for SU 6656

Solubility for SU 6656

Dilution Calculator

Reconstitution Calculator

References for SU 6656

Product Documents for SU 6656

COA

Certificate of Analysis

SDS

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