TC AQP1 1

Name: TC AQP1 1
Brand: Tocris Bioscience
SKU: 5412

Tocris Bioscience, part of Bio-Techne | Catalog # 5412

Citations (3)

COA / SDS

Aquaporin 1 (AQP1) channel blocker

Key Product Details

Description:	Aquaporin 1 (AQP1) channel blocker
Chemical Name:	3,3'-(1,3-Phenylene)bis(2-propenoic acid)
Purity:	≥98% (HPLC)
Molecular Weight:	218.211

View Full Technical Details for TC AQP1 1

Technical Data
Citations

Biological Activity for TC AQP1 1

TC AQP1 1 is an aquaporin 1 (AQP1) channel blocker (IC₅₀ = 8 μM). Inhibits water flux in Xenopus oocytes.

Technical Data for TC AQP1 1

M. Wt	218.211
Formula	C₁₂H₁₀O₄
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	37710-81-9
PubChem ID	794091
InChi Key	KRXUBZPHAPGHPE-YDFGWWAZSA-N
Smiles	O=C(O)/C=C/C1=CC(/C=C/C(O)=O)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TC AQP1 1

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	21.82	100

Preparing Stock Solutions for TC AQP1 1

The following data is based on the product molecular weight 218.211.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.58 mL	22.91 mL	45.83 mL
5 mM	0.92 mL	4.58 mL	9.17 mL
10 mM	0.46 mL	2.29 mL	4.58 mL
50 mM	0.09 mL	0.46 mL	0.92 mL

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Reconstitution Calculator

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References for TC AQP1 1

References are publications that support the biological activity of the product.

Seeliger Discovery of novel human aquaporin-1 blockers. ACS Chem.Biol. 2013 PMID: 23113556