TC-E 5002

Name: TC-E 5002
Brand: Tocris Bioscience
SKU: 5089

Tocris Bioscience, part of Bio-Techne | Catalog # 5089

Citations (2)

COA / SDS

Selective KDM2/7 inhibitor

Key Product Details

Chemical Name:	N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine
Purity:	≥98%

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Technical Data
Citations

Biological Activity for TC-E 5002

TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor (IC₅₀ values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro.

Technical Data for TC-E 5002

Formula	C₁₅H₂₇NO₄
Storage	Store at -20°C
Purity	≥98%
CAS Number	1453071-47-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TC-E 5002

Solubility

Soluble Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO

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References for TC-E 5002

References are publications that support the biological activity of the product.

Suzuki et al. Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity. J.Med.Chem., 2013;56 PMID: 23964788

TC-E 5002

Tocris Bioscience, part of Bio-Techne | Catalog # 5089

Key Product Details

Biological Activity for TC-E 5002

Technical Data for TC-E 5002

Solubility for TC-E 5002

Dilution Calculator

Reconstitution Calculator

References for TC-E 5002

Product Documents for TC-E 5002

COA

Certificate of Analysis

SDS

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