TCS HDAC6 20b

Name: TCS HDAC6 20b
Brand: Tocris Bioscience
SKU: 4805

Tocris Bioscience, part of Bio-Techne | Catalog # 4805

Citations (1)

COA / SDS

Selective HDAC6 inhibitor

Discontinued Product

4805 has been discontinued. View all Class II Histone Deacetylases Inhibitors products.

Key Product Details

Description:	Selective HDAC6 inhibitor
Chemical Name:	2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.1^3,7]dec-1-ylamino)heptyl] ester
Purity:	≥98% (HPLC)
Molecular Weight:	480.7

View Full Technical Details for TCS HDAC6 20b

Technical Data
Citations

Biological Activity for TCS HDAC6 20b

TCS HDAC6 20b is a selective inhibitor of histone deacetylase 6 (HDAC6). Inhibits HCT116 growth in combination with taxol (Cat. No. 1097). Also inhibits growth of MCF-7 cells stimulated by estrogen.

Technical Data for TCS HDAC6 20b

M. Wt	480.7
Formula	C₂₆H₄₄N₂O₄S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	956154-63-5
PubChem ID	23636017
InChi Key	DQZMLPMCOMRJOR-MOVGKWKRSA-N
Smiles	O=C([C@@H](NC(OC(C)(C)C)=O)CCCCCSC(C(C)C)=O)NC1(CC3C2)CC(C3)CC2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for TCS HDAC6 20b

References are publications that support the biological activity of the product.

Itoh Design, synthesis, structure-selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J.Med.Chem. 2007 PMID: 17929798

TCS HDAC6 20b

Tocris Bioscience, part of Bio-Techne | Catalog # 4805

Key Product Details

Biological Activity for TCS HDAC6 20b

Technical Data for TCS HDAC6 20b

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for TCS HDAC6 20b

Product Documents for TCS HDAC6 20b

COA

Certificate of Analysis

SDS

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