Temsirolimus

Biological Activity for Temsirolimus

Technical Data for Temsirolimus

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Temsirolimus

References for Temsirolimus

References are publications that support the biological activity of the product.

• Wang et al. Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus). DNA Cell Biol., 2012;31:1095 PMID: 22320865
• Wu L et al. Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts. Cancer Res., 2005;65:2825 PMID: 15805283
• Li et al. The novel mTOR inhibitor CCI-779 (temsirolimus) induces antiproliferative effects through inhibition of mTOR in Bel-7402 liver cancer cells. Cancer Cell Int., 2013;13 PMID: 23537100
• Galluzzi et al. Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles. Nat.Rev.Drug.Discov., 2017; PMID: 28529316
• Del Bufalo et al. Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsiro. Cancer Res., 2006;66:5549 PMID: 16740688