Tertiapin LQ

Name: Tertiapin LQ
Brand: Tocris Bioscience
SKU: 4339

Tocris Bioscience, part of Bio-Techne | Catalog # 4339

COA / SDS

Selective Kir1.1 blocker; derivative of tertiapin-Q (Cat. No. 1316)

Discontinued Product

4339 has been discontinued. View all Inward Rectifier Potassium Channel Blockers products.

Key Product Details

Description:	Selective K_ir1.1 blocker; derivative of tertiapin-Q (Cat. No. 1316)
Molecular Weight:	2428.03

View Full Technical Details for Tertiapin LQ

Technical Data
Citations

Biological Activity for Tertiapin LQ

Tertiapin LQ is a blocker of K_ir1.1 channels; displays >250-fold selectivity for K_ir1.1 (K_d values are 1.1, 274 and 361 nM for K_ir1.1, K_ir3.1/3.2 and K_ir3.1/3.4 respectively). Derivative of tertiapin-Q (Cat. No. 1316).

Technical Data for Tertiapin LQ

M. Wt	2428.03
Formula	C₁₀₆H₁₇₉N₃₃O₂₄S₄
Single Letter Sequence	ALCNCNRIIIPLQCWKKCGKK (Modifications: Disulfide bridge between 3 - 14, 5 - 18, Lys-21 = C-terminal amide)
Storage	Store at -20°C
PubChem ID	90488935
InChi Key	WUMIWMIQOSXVPZ-ZPWFPUPGSA-N
Smiles	[H]N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CNC4=C3C=CC=C4)NC2=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Tertiapin LQ

References are publications that support the biological activity of the product.

Ramu Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K⁺ channels. Proc.Natl.Acad.Sci.USA 2008 PMID: 18669667

Tertiapin LQ

Tocris Bioscience, part of Bio-Techne | Catalog # 4339

Key Product Details

Biological Activity for Tertiapin LQ

Technical Data for Tertiapin LQ

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Tertiapin LQ

Product Documents for Tertiapin LQ

COA

Certificate of Analysis

SDS

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