Thalidomide 4'-ether-PEG3-amine

Name: Thalidomide 4'-ether-PEG3-amine
Brand: Tocris Bioscience
SKU: 6950

Tocris Bioscience, part of Bio-Techne | Catalog # 6950

COA / SDS

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Key Product Details

Description:	Cereblon ligand with PEG linker and terminal amine for onward chemistry
Alternative Names:	Thalidomide - linker 11
Chemical Name:	4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95% (HPLC)
Molecular Weight:	485.92

View Full Technical Details for Thalidomide 4'-ether-PEG3-amine

Technical Data
Citations

Biological Activity for Thalidomide 4'-ether-PEG3-amine

Thalidomide 4'-ether-PEG3-amine is a functionalized cereblon ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Thalidomide - linker 11

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for Thalidomide 4'-ether-PEG3-amine

M. Wt	485.92
Formula	C₂₁N₂₇N₃O₈.HCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2387510-82-7
PubChem ID	146018962
InChi Key	NDHMOOQETYCWFG-UHFFFAOYSA-N
Smiles	O=C(N1C(CC2)C(NC2=O)=O)C3=C(C1=O)C(OCCOCCOCCOCCN)=CC=C3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for Thalidomide 4'-ether-PEG3-amine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.