TP 472

Name: TP 472
Brand: Tocris Bioscience
SKU: 6000

Tocris Bioscience, part of Bio-Techne | Catalog # 6000

Citations (25)

COA / SDS

Potent BRD9/7 inhibitor

Key Product Details

Chemical Name:	3-(6-Acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide
Purity:	≥98%

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Technical Data
Citations

Biological Activity for TP 472

TP 472 is a potent BRD9/7 inhibitor (K_d values are 33 and 340 nM, respectively) Exhibits >30-fold selectivity for BRD9 over other bromodomains except BRD7. Cell permeable and active in vivo.

Negative Control also available.

Technical Data for TP 472

Formula	C₂₀H₁₉N₃O₂
Storage	Store at -20°C
Purity	≥98%
CAS Number	2079895-62-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TP 472

Solubility

Soluble Soluble to 50 mM in DMSO

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References for TP 472

References are publications that support the biological activity of the product.

Hohmann and Vakoc et al. A rationale to target the SWI/SNF complex for cancer therapy. Trends Genet., 2014;30:356 PMID: 24932742

TP 472

Tocris Bioscience, part of Bio-Techne | Catalog # 6000

Key Product Details

Biological Activity for TP 472

Technical Data for TP 472

Solubility for TP 472

Dilution Calculator

Reconstitution Calculator

References for TP 472

Product Documents for TP 472

COA

Certificate of Analysis

SDS

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