UK 14,304 tartrate

Biological Activity for UK 14,304 tartrate

Technical Data for UK 14,304 tartrate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for UK 14,304 tartrate

References for UK 14,304 tartrate

References are publications that support the biological activity of the product.

• NZ Gungor, R Yamamoto, D Pare Glutamatergic and gabaergic ventral BNST neurons differ in their physiological properties and responsiveness to noradrenaline Neuropsychopharmacology, 2018;0(0):. 2018 PMID: 29704000
• Cambridge UK-14,304, a potent and selective alpha2-gonist for the characterisation of alpha-adrenoceptor subtypes. Eur.J.Pharmacol., 1981;72:413 PMID: 6115759
• Andorn et al. Specific [³H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α₂-adrenergic selectivity and different affinities for GTP. Life Sci., 1988;43:1805 PMID: 2904634
• Macdonald et al. Gene targeting - homing in on α₂-adrenoceptor-subtype function. TiPS, 1997;18:211 PMID: 9227000
• Chopin et al. Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxyDA lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther., 1999;288:798 PMID: 9918591