VH 032 amide-alkylC9-acid

Name: VH 032 amide-alkylC9-acid
Brand: Tocris Bioscience
SKU: 7404

Tocris Bioscience, part of Bio-Techne | Catalog # 7404

COA / SDS

VHL ligand with alkyl linker and terminal acid for onward chemistry

Key Product Details

Description:	VHL ligand with alkyl linker and terminal acid for onward chemistry
Alternative Names:	(S,R,S)-AHPC-C9-COOH
Chemical Name:	11-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecanoic acid
Purity:	≥95% (HPLC)
Molecular Weight:	628.83

View Full Technical Details for VH 032 amide-alkylC9-acid

Technical Data
Citations

Biological Activity for VH 032 amide-alkylC9-acid

Functionalized von-Hippel-Lindau protein (VHL) ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkylC9 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for VH 032 amide-alkylC9-acid

M. Wt	628.83
Formula	C₃₃H₄₈N₄O₆S
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2172819-78-0
PubChem ID	134184031
InChi Key	MTQZLQCVZFDQOZ-DIIXFEDBSA-N
Smiles	CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCCCCCCCCC(O)=O)=O)=O)O)=O)SC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Product Documents for VH 032 amide-alkylC9-acid

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.