XAV 939

Biological Activity for XAV 939

Technical Data for XAV 939

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for XAV 939

References for XAV 939

References are publications that support the biological activity of the product.

• Q Yu, Z Xia, EC Liong, GL Tipoe Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF?kappaB/IkappaBalpha pathways in the skeletal muscle of rats fed with a high fat diet Mol Med Rep, 2019;20(6):4963-4972. 2019 PMID: 31702809
• Dambrot C, Braam S, Tertoolen L, Birket M, Atsma D, Mummery C Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes. J Cell Mol Med, 2014;18(8):1509-18. 2014 PMID: 24981391
• Jansen S, Holman R, Hedemann I, Frankes E, Elzinga C, Timens W, Gosens R, de Bont E, Schmidt M Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via beta-catenin stabilization. J Cell Mol Med, 2015;19(1):210-26. 2015 PMID: 25266063
• Bone R, Bailey C, Wiedermann G, Ferjentsik Z, Appleton P, Murray P, Maroto M, Dale J Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM. Development, 2014;141(24):4806-16. 2014 PMID: 25468943
• Bai J, Liu Z, Xu Z, Ke F, Zhang L, Zhu H, Lou F, Wang H, Fei Y, Shi Y, Wang H Epigenetic downregulation of SFRP4 contributes to epidermal hyperplasia in psoriasis. J Immunol, 2015;194(9):4185-98. 2015 PMID: 25825452
• Yuen T, Silbereis J, Griveau A, Chang S, Daneman R, Fancy S, Zahed H, Maltepe E, Rowitch D Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis. Cell, 2014;158(2):383-96. 2014 PMID: 25018103
• JGW Smith, T Owen, JR Bhagwan, D Mosqueira, E Scott, I Mannhardt, A Patel, R Barriales-, L Monserrat, A Hansen, T Eschenhage, SE Harding, S Marston, C Denning Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits Stem Cell Reports, 2018;0(0):. 2018 PMID: 30392975
• ZZ Wei, JY Zhang, TM Taylor, X Gu, Y Zhao, L Wei Neuroprotective and regenerative roles of intranasal Wnt-3a Administration after focal ischemic stroke in mice J. Cereb. Blood Flow Metab., 2017;0(0):271678X177026. 2017 PMID: 28430000
• Huang et al. Tankyrase inhibition stabilizes axin and antagonizes wnt signalling. Nature, 2009;461:614 PMID: 19759537
• Adler Inhibiting wnt signaling. Sci.Signal., 2009;91
• Wang et al. Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/β-catenin signaling. ACS Chem. Biol., 2010;6:192 PMID: 21077691