EGTA

Name: EGTA
Brand: Tocris Bioscience
SKU: 2807
Rating: 5 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2807

(2)

Citations (149)

COA / SDS

Calcium chelating agent

Key Product Details

Description:	Calcium chelating agent
Chemical Name:	Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid
Molecular Weight:	380.35

View Full Technical Details for EGTA

Technical Data
Citations / Reviews (2)

Biological Activity for EGTA

EGTA is a calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.

Technical Data for EGTA

M. Wt	380.35
Formula	C₁₄H₂₄N₂O₁₀
Storage	Store at RT
CAS Number	67-42-5
PubChem ID	6207
InChi Key	DEFVIWRASFVYLL-UHFFFAOYSA-N
Smiles	O=C(CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for EGTA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	1M NaOH	38.03	100

Preparing Stock Solutions for EGTA

The following data is based on the product molecular weight 380.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.63 mL	13.15 mL	26.29 mL
5 mM	0.53 mL	2.63 mL	5.26 mL
10 mM	0.26 mL	1.31 mL	2.63 mL
50 mM	0.05 mL	0.26 mL	0.53 mL

Molarity Calculator

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Reconstitution Calculator

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References for EGTA

References are publications that support the biological activity of the product.

Fisher Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochem.Biophy.Res.Comms.
Boullerne Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. J.Neurosci.Res. 2001 PMID: 11169622