The Simple Way to Targeted Protein Degradation Analysis

Simple Western technology provides critical information to run quantitative DC₅₀ curves with a high throughput protein degradation western blot workflow and reproducible and fully quantitative data. Simple Western instruments provide automated Western blotting capabilities enhance accuracy, ensure data quality, and deliver results. Our systems integrate easily in PROTAC and Molecular Glue Degrader screening assays while providing you the flexibility of seamless transferability of methods and an open platform.

• High-throughput western analysis of up to 100 samples in 3 hands-free hours
• Fast and accurate DC₅₀ and D_max measurements with 3 µL lysate samples 
• Automated degrader screening and granular time course and dose-response experiments
• Fully quantitative protein expression data
• Multiplex analysis in chemiluminescence and fluorescence channels
• Built-in total protein normalization

Innovative Approaches to Degrader Screening

Simple Western Technology provides fully automated protein degradation analysis, delivering reliable, reproducible quantitative protein expression data with size resolution for added specificity. Learn how to screen for PROteolysis-TArgeting Chimeras (PROTACs) using the Simple Western Platform. Leo, the latest Simple Western Instrument, streamlines PROTAC assessment by fully automating protein expression analysis in 96 lysate samples within just 3 hours, enabling efficient screening of targets like the Androgen Receptor (AR) for proteasomal degradation.