Characterizing tumor‐infiltrated immune cells with spatial context using RNAscope™ ISH‐immunohistochemistry co‐detection workflow in FFPE tissues

The new RNAscope-ISH-IHC co-detection workflow and reagents enable optimized simultaneous visualization of RNA and protein targets by enhancing the compatibility of antibodies, including many previously incompatible antibodies with RNAscope.

• The new integrated co-detection assays allows multi-omic profiling in-situ with single cell resolution.
• Combining RNAscope target probes with immune cell marker antibodies enabled detection of key tumor-infiltrating immune cells.
• The new RNA-protein Co-detection Ancillary kit improves IHC antibody compatibility with RNAscope and BaseScope assays creating an extremely powerful technique to answer unique biological questions.