Comparing SDS-PAGE with Maurice CE-SDS for Protein Purity Analysis

The accurate and quantitative analysis of product purity is a fundamental component of effective development of a biotherapeutic protein. But without consistent techniques and high-quality, reproducible results, it is difficult to correctly assess the product’s efficacy and/or safety, potentially delaying, even jeopardizing, its approval.

In this Application Note, we compare Maurice™ CE-SDS with SDS PAGE in parallel, using a standard and a commercially available therapeutic monoclonal antibody (mAb) under varying conditions. The comparative results highlight the advantages of Maurice CE-SDS over SDS PAGE for routine product purity characterization.