Comparing the Performance of the Maurice and MauriceFlex Systems for Charge Heterogeneity Analysis
Application NotesThe Maurice™ and MauriceFlex™ systems both enable icIEF and CE-SDS assays, with icIEF fractionation as an additional capability on the MauriceFlex system. In this study, the performance of Maurice and MauriceFlex systems were compared for analytical icIEF assays.
Four different molecules – bispecific antibody, mAb, fusion protein, and AAV were analyzed.
Percent peak area and apparent pI values were measured and compared between instruments.
For each of the four molecules, icIEF assays generated comparable results between the Maurice and MauriceFlex systems, demonstrating the suitability of either system for use across different stages of drug development.
