Characterization of Monoclonal Antibodies by CE-SDS: Maurice Versus LabChip

In this application note, we compare Maurice^TM against PerkinElmer's LabChip GXII Touch, a chip-based electrophoretic separation system. Under reduced and non-reduced conditions, we evaluate CE-SDS separation using a reference mAb from the National Institute of Standards and Technology (NIST). Maurice and LabChip are assessed for their performance on linearity, sensitivity, precision, reproducibility and resolution, with the technological approach, workflow and data quality outlined for easy comparison.