Parkinson’s Disease Research Product Guide
Product Guides and ListingsParkinson’s disease is a progressive neurodegenerative disease characterized by disturbances in neurotransmitter signaling that progresses to synaptic loss and loss of dopaminergic neurons in the substantia nigra pars compacta. It impairs motor learning, function, and coordination; non-motor symptoms may manifest as early as 20 years before the first motor symptoms.
There are both environmental and genetic components to Parkinson’s disease, with mutations in several genes being linked to disease development and pathogenesis. The proteins encoded by these genes are being investigated as potential therapeutic targets.
Some featured topics in the Parkinson’s disease product guide include:
- α-synuclein
- Lysosomal Dysregulation
- Mitochondrial Dysfunction
- Depletion of Dopaminergic Signaling
- Stem Cells