Specific Detection of RNA Expression and Distribution in Brain Using RNAscope™ Technology

Understanding the molecular mechanisms of neurological disease development and progression is necessary to identify key pathogenic steps, and thereby discover new potential therapeutic targets through a combination of epidemiology-related neuropathology, biomarkers for clinical trials, and experimental studies. RNAscope™ in situ hybridization (ISH) technology enables cell- and tissue-specific localization of RNA transcripts quickly and precisely for functionally important targets in the nervous system. With RNAscope ISH assays, you can turn any gene specifically expressed by a particular cell lineage into an endogenous marker for neuronal cell types and tissues.