Unlocking the power of organoids in personalized medicine
Posted February 14, 2024
"It is key technologies like RNAscope used after scRNAseq that is enabling us to visualize the genes in the context of the whole tissue...and pave the way for therapeutic approaches to intestinal diseases."
- Dr Hans Clevers & Dr Joep Beumer, Hubrecht Institute, Utrecht University
Organoids are used to study many diseases that otherwise could not have been studied using traditional cell lines. Using RNAscope™ ISH technology to understand spatial gene expression and heterogeneity at the single-cell level in sub populations of enteroendocrine cells in the gut epithelium.