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Webinar: Use of RNAscope ISH Services for T Cell Therapy Detection & Quantification

Webinar Summary


2020 Dec 15 PAS Webinar: Use of RNAscope ISH Services for T Cell Therapy Detection & Quantification

Presented by:
Christopher Bunker, Ph.D., MBA
Senior Director, Business Development,
Advanced Cell Diagnostics, a Bio-Techne Brand

Outline:
T Cell Therapy Detection and Quantification in Solid Tumors by RNAscope™ in situ hybridization.

RNAscope ISH is the only method for specific detection of engineered CAR-T and TCR-T cell therapies in clinical trial patient biopsies. RNAscope probes targeting viral untranslated regions (UTRs) common to CAR and TCR mRNAs, enable specific detection and quantification of CAR/TCR-T cells in the tumor microenvironment (TME). RNAscope UTR probes are easily multiplexed with probes to assess activation, e.g.,